Basal Ganglia Hemorrhage: Minimally Invasive and Neuro-Navigation Guided Treatment by Injection of Recombinant Tissue-Type Plasminogen Activator (rtPA)

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Basal Ganglia Hemorrhage: Minimally Invasive and Neuro-Navigation Guided Treatment by Injection of Recombinant Tissue-Type Plasminogen Activator (rtPA)

Objective: Since open surgical evacuation of basal ganglia hemorrhage (BGH) as had been proved did not lead to the desired benefit for the patients, we used minimally invasive clot lysis by injection of recombinant tissue-type plasminogen activator (rtPA). Methods: Patients with spontaneous BGH with or without accompanied intraventricular hemorrhage were included in the study. Following diagnos...

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Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema.

BACKGROUND AND PURPOSE Perihematomal edema (PHE) can worsen outcomes after intracerebral hemorrhage (ICH). Reports suggest that blood degradation products lead to PHE. We hypothesized that hematoma evacuation will reduce PHE volume and that treatment with recombinant tissue-type plasminogen activator (rt-PA) will not exacerbate it. METHODS Minimally invasive surgery and rt-PA in ICH evacuatio...

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Destruction of Recombinant Tissue Plasminogen Activator (rtPA) -Loaded Echogenic Liposomes under Dual Frequency Sonication

Background:Echogenic liposomes (ELIPs) encapsulate drugs and gas bubbles within lipid vesicles. The destruction of ELIPs in response to MHz and kHz ultrasound waves has been studied previously. Applying ultrasound above a certain threshold causes encapsulated gas bubbles destruct rapidly by fragmentation or more slowly by acoustically driven diffusion. This study compares the d...

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Recombinant tissue plasminogen activator in the treatment of suprachoroidal hemorrhage

BACKGROUND Suprachoroidal hemorrhages are a vision-threatening complication, and poor visual outcome is correlated with increasing hemorrhage complexity. The recommended time of surgical drainage is 10-14 days after the hemorrhage begins to liquefy. We describe a case in which recombinant tissue plasminogen activator (r-tPA), alteplase, is injected within the suprachoroidal space before surgery...

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Successful Management of Reversible Cerebral Vasoconstriction Syndrome-Induced Intracerebral Hemorrhage with Minimally Invasive Surgery Plus Recombinant Tissue-Type Plasminogen Activator

RCVS: Reversible Cerebral Vasoconstriction Syndrome; rtPA: recombinant tissue Plasminogen Activator; GCS: Glasgow Coma Scale; CT: Computed Tomography; ICH: Intracerebral Hemorrhage; MRI: Magnetic Resonance Imaging; MRR: MR Renography; ACA: Anterior Cerebral Artery; MIS: Minimally Invasive Surgery; TCD: Transcranial Doppler; ICU: Intensive Care Unit; MISTIE: Minimally Invasive Surgery plus rt-PA...

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ژورنال

عنوان ژورنال: Journal of Neurological Disorders

سال: 2013

ISSN: 2329-6895

DOI: 10.4172/2329-6895.1000158